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Levothyroxine Hormone Replacement Thyroid hormone replacement therapy for hypothyroidism and Hashimotos disease involves prescribing synthetic levothyroxine (T4)

This naturally occurring substance is found in all mammalian tissues, especially striated muscle, and is required in energy metabolism, such as the oxidation of fatty acids, facilitating the aerobic metabolism of carbohydrates, and enhancing the excretion of certain organic acids

Additionally, B12 is involved in energy metabolism, aiding in the conversion of food into energy, and has implications for mood regulation through its role in neurotransmitter synthesis

By consolidating the management strategies to address both the psychological and physiological impacts of diabetes, healthcare providers can offer more holistic care that potentially improves both health outcomes and quality of life for patients

However, this difference was not statistically significant (p=0.270)