SPTC2 Rabbit Polyclonal Antibody, 20ul Vacuum Filter Pseudogenes of this gene have

Pseudogenes of this gene have been identified on multiple chromosomes

It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates

A related pseudogene has been identified on chromosome 7

Binds to DNA sequences containing the consensus nucleotide core sequence GGAA

also designated precerebellin 1 or Cbln1

SPTC2 Rabbit Polyclonal Antibody, 20ul Vacuum Filter Pseudogenes of this gene haveThis gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase which consists of two different subunits is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal 5 prime phosphate dependent condensation of L serine and palmitoyl CoA to 3 oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.