Human Chondroitin Sulfate Proteoglycan 4, CSPG4 ELISA Kit , 96T Buffers & Solutions The duplicated copy of this

The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein

This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors

PDGFRB is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor

Further processing of the beta subunit results in the formation of the M10 peptide

5)biphosphate

Human Chondroitin Sulfate Proteoglycan 4, CSPG4 ELISA Kit , 96T Buffers & Solutions The duplicated copy of thisProteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N terminus growth factors, extracellular matrix proteases modulating their activity.