CARD 14 Polyclonal Antibody, 100ul Aspirating Pipets Both TAL1 and LMO2 have

Both TAL1 and LMO2 have been associated with T-cell acute lymphoblastic leukemia (T-ALL)

It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form

a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane

The encoded preproprotein undergoes proteolytic processing to generate one or more mature isoforms before secretion from the parotid glands

The protein kinase domain is predicted to be catalytically inactive

CARD 14 Polyclonal Antibody, 100ul Aspirating Pipets Both TAL1 and LMO2 haveCARD14 (caspase recruitment domain family member 14) encodes a caspase recruitment domain containing protein that is a member of the membrane associated guanylate kinase (MAGUK) family of proteins. Members of this protein family are scaffold proteins that are involved in a diverse array of cellular processes including cellular adhesion, signal transduction and cell polarity control. This protein has been shown to specifically interact with BCL10, a