IGFBP3 Polyclonal Antibody, 50ul[BT-AP04388] Reservoirs Mutations in this gene cause

Mutations in this gene cause primary ciliary dyskinesia 1| a disease arising from dysmotility of motile cilia and sperm

Alternatively spliced transcript variants encoding multiple isoforms have been observed for CASP7

and inside the kinetochore corona

The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors

and may play a role in cell interactions with the extracellular matrix

IGFBP3 Polyclonal Antibody, 50ul[BT-AP04388] Reservoirs Mutations in this gene causeIGFBP3 is a member of the insulin like growth factor binding protein (IGFBP) family and encodes Insulin like growth factor binding protein 3 with an IGFBP domain and a thyroglobulin type I domain. The protein forms a ternary complex with insulin like growth factor acid labile subunit (IGFALS) and either insulin like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half life of IGFs and altering their interaction