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Newer treatment modalities targeting the GH resistance with recombinant human IGF-1 (rhIGF-1), recombinant human IGFBP3 (rhIGFBP3) and IGFBP displacers are under investigation and may prove to be more effective in treating growth failure in CKD

Taken together, these findings suggest that alleviation of the weight loss and inflammatory exacerbation associated with UC resulted in a significant decline in mortality in the Si-DSS group compared with that in the Con-DSS group (Table 1)