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Important Caveats: This observation is anecdotal, not registry-derived It is not a substitute for controlled epidemiology It provides real-world context consistent with MTC rarity and absence of compelling causal signals in highest-quality human evidence Clinical Significance: In a practice seeing more thyroid cancer than anywhere globally, we are not observing an MTC wave in GLP-1 users

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Adequate protein intake, iron and zinc supplementation, and biotin can support faster recovery

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6.7% of patients taking GLP-1 developed NAION compared to 0.8% of patients taking other medications