ALK-1 Polyclonal Antibody, 50ul[BT-AP00374] Pipette Filler The protein encoded by MAP2K7

The protein encoded by MAP2K7 (mitogen-activated protein kinase kinase 7) is a dual specificity protein kinase that belongs to the MAP kinase kinase family

some of which are disease-associated mutations

MIM 613213) (Zhu et al

This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function

The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation

ALK-1 Polyclonal Antibody, 50ul[BT-AP00374] Pipette Filler The protein encoded by MAP2K7ACVRL1 encodes a type I cell surface receptor for the TGF beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine threonine kinase subdomains, a glycine and serine rich region (called the GS domain) preceding the kinase domain, and a short C terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor like kinase proteins