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Trk B Polyclonal Antibody, 100ul[BT-AP09214] Cell Transfection SH3PXD2A contains an amino-terminal PX

SKU: 75622392461

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Trk B Polyclonal Antibody, 100ul[BT-AP09214] Cell Transfection SH3PXD2A contains an amino-terminal PXNTRK2 encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in NTRK2 have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.

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Description

SH3PXD2A contains an amino-terminal PX domain followed by five SH3 domains

PTK2B encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway

which is involved in vesicle trafficking

The protein is localized to the nucleus

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Trk B Polyclonal Antibody, 100ul[BT-AP09214] Cell Transfection SH3PXD2A contains an amino-terminal PXNTRK2 encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in NTRK2 have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.

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