BMP-6 Polyclonal Antibody, 50ul[BT-AP00929] ROS/Nitric Oxide Detection Mutations in this gene result

Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis

The heterodimeric complex may function in the inhibition of activin A signaling

tissue specificity:According to PubMed:17256767 highly expressed in the thymus with lower levels in the placenta

Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site| 5'-TTTC

The selenocysteine is encoded by the UGA codon that normally signals translation termination

BMP-6 Polyclonal Antibody, 50ul[BT-AP00929] ROS/Nitric Oxide Detection Mutations in this gene resultBMP6 encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide linked homodimer. This protein regulates a wide range of biological processes including