TCF-3 Polyclonal Antibody, 100ul[BT-AP08892] Metabolic enzymes tool compounds Variations in the number of

Variations in the number of 23 amino acid repeats in the neck domain of this protein are rare but have a significant impact on ligand binding ability

Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes

proprotein convertases remove that section to activate the enzyme

Mutations in this

Alternative promoter usage and alternative splicing result in dozens of transcript variants

TCF-3 Polyclonal Antibody, 100ul[BT-AP08892] Metabolic enzymes tool compounds Variations in the number ofTCF3 encodes a member of the E protein (class I) family of helix loop helix transcription factors. E proteins activate transcription by binding to regulatory E box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA binding (class IV) helix loop helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development.