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The yeast has evolved sophisticated survival mechanisms biofilm production, phenotypic switching, and immune evasion that render isolated antifungal approaches inadequate for the vast majority of patients

When compared to placebo, patients receiving cagrilintide alone lost an average of 5-10% of their body weight

To confirm whether the lipolytic action of AOD 9604 might merely be associated with the increased lipolytic receptor levels, additional studies were carried out where AOD 9604 was given to mice with knocked out lipolytic receptors