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[1] [2] Other considerations include nausea and vomiting , common side effects of tirzepatide that may be exacerbated by anesthesia and opioid analgesics used perioperatively

If small particulates are still observed after 15 minutes, incubate at room temperature for an additional 30 minutes, and leave the vial at 2C - 8C overnight

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This is standard practice in clinical trials, which are designed to first establish safety in a "best-case scenario" population before results can be more broadly applied

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