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Touitou E, Dayan N, Bergelson L, Godin B, Eliaz M

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Melanotan 2 (MT-II) is a cyclic lactam analogue of -MSH with non-selective agonist activity at MC1R, MC3R, MC4R, and MC5R receptors

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We removed exendin-4(939) from the structure of the exendin-4(939)-ECD complex (Protein Data Bank code 3C59) and used the apo-form of GLP-1R ECD as the search model for the molecular replacement

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