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In a study of more than 240,000 people, heavier individuals were significantly more likely to form stones than lean ones.[3] The reason is biochemical: obesity and insulin resistance push the kidney to excrete more calcium, oxalate, and uric acid, and they make the urine more acidic close to a perfect recipe for stone crystals

Despite a minefield of resources and imitators to navigate, Levites feels encouraged by their desire to learn facts from fiction

Clinical trials tell the story in numbers

Landmark studies in patients with T2DM including Veteran Affairs Diabetes trial (VADT), the Action in Diabetes and Vascular Disease: Preterax and Diamicron MR controlled Evaluation (ADVANCE) trial, and the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial have provided consistent evidence that intensive glycemic control is the path to follow

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