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However, the effect seemed to diminish over time [7]

This angiogenic effect explains much of why BPC-157 works so broadly: better blood supply to injured tissue accelerates virtually every downstream repair process

doi: 10.1038/s41591-019-0406-6

Plant Gene Trait 7(11):117 Innocenti G, Pucciariello C, Le Gleuher M, Hopkins J, Stefano M, Delledonne M, Puppo A, Baudouin E, Frendo P (2007) Glutathione synthesis is regulated by nitric oxide in Medicagotruncatula roots

GPX Activity (U/L) = (delta-OD S - delta-OD B ) / (Slope x 4 min) x 1000 x n, where n is the dilution factor

It may reach the correct site, but may not be targeted toward the specific agent responsible for oxidative damage, as observed in the case of vitamin E that inhibits lipid peroxidation, but may not prevent the increased oxidative DNA, RNA, and protein damage seen in Alzheimers disease (Pratic, 2008)