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So the delivery of GPx3 to breast tumor tissues through hiPSC-MSCs or other methods may promote its expression, and reduce the influence of ROS on the progression of breast cancer accordingly, finally achieve the goal of treating breast cancer

Within the cell, approximately 90% of glutathione is located in the cytosol, 10% in the mitochondria and a small percentage in the endoplasmic reticulum [29]

doi: 10.1016/j.ccell.2022.08.016 108 XueJLiRZhaoXMaCLvXLiuLet al

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After 12 weeks of treatment, gut microbiome -diversity diverged significantly between responders and non-responders, and multivariate analyses confirmed that baseline levels of B