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APLP-1 Polyclonal Antibody, 100ul Thermal Control An important paralog of this

SKU: 64848674863

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PLN141.00 PLN190.00

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APLP-1 Polyclonal Antibody, 100ul Thermal Control An important paralog of thisAPLP1 encodes a member of the highly conserved amyloid precursor protein gene family. The amyloid like protein 1 is a membrane associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development.

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Description

An important paralog of this gene is HAP1

Promotes selective NLRP3 inflammasome assembly in response to microbial and soluble

It is a C-type lectin with mannose binding specificity

In migrating cells

Diseases associated with PRDM12 include neuropathy

APLP-1 Polyclonal Antibody, 100ul Thermal Control An important paralog of thisAPLP1 encodes a member of the highly conserved amyloid precursor protein gene family. The amyloid like protein 1 is a membrane associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development.

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