glp 1 cardiac benefit GLP-1 receptor agonists and cardiovascular outcome trials: An update Benefits and drawbacks of GLP-1

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You should also consult a doctor in the following cases 7 : Before any planned surgery or procedure, as GLP-1 RAs may affect gastric emptying and fasting requirements

Currently licensed GLP-1 receptor agonists in the UK include: Exenatide (Bydureon) once-weekly formulation (note: Byetta twice-daily formulation has been discontinued in the UK) Liraglutide (Victoza for diabetes

At a glance Most common cause / nausea and vomiting from GLP-1 GI side effects reducing fluid intake and increasing fluid loss Incidence of nausea (semaglutide 2.4 mg) / approximately 44% of participants in the STEP-1 trial reported nausea Incidence of vomiting (semaglutide 2.4 mg) / approximately 24% in STEP-1, the primary driver of acute fluid loss Incidence of diarrhea (semaglutide 2.4 mg) / approximately 30% in STEP-1, contributing to electrolyte depletion First-line treatment / oral rehydration with electrolytes