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PFI-4 - BRPF1 Bromodomain Inhibitor. CAS# 900305-37-5 0020 1 μM) inhibits EGFR potently

PFI-4 - BRPF1 Bromodomain Inhibitor. CAS# 900305-37-5 0020 1 μM) inhibits EGFR potently

Name: PFI-4 - BRPF1 Bromodomain Inhibitor. CAS# 900305-37-5 0020 1 μM) inhibits EGFR potently
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SKU: 24191751807
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SKU: 24191751807

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PFI-4 - BRPF1 Bromodomain Inhibitor. CAS# 900305-37-5 0020 1 μM) inhibits EGFR potentlyPFI 4, CAS No. 900305 37 5, is a potent, selective and cell permeable BRPF1 bromodomain inhibitor. It binds to BRPF1B with a Kd of 13 nM (ITC). It has general >100 fold selectivity against other bromodomains including BRPF2, BRPF3 and BRD4. It reduces recovery time in triple BRD cell construct in FRAP and is potent in cells with IC50 250 nM, while showing no effect on BRPF1A. Product information CAS Number: 900305 37 5 Molecular Weight: 380. 44

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Description

1 μM) inhibits EGFR potently and irreversibly

Small-Molecule Inducer of β Cell Proliferation Identified by High-Throughput Screening

Solubility: DMSO: 77 mg/mL (185

Chemical Name: 3-((3R

an IkappaB ubiquitination inhibitor

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