HIF-1 Beta/ARNT Monoclonal Antibody(4C5), 20ul Nucleic Acid Amplification KLHL3 is ubiquitously expressed and

KLHL3 is ubiquitously expressed and encodes kelch like family member 3 which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus

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Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease

Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease)

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HIF-1 Beta/ARNT Monoclonal Antibody(4C5), 20ul Nucleic Acid Amplification KLHL3 is ubiquitously expressed andThis gene encodes a protein containing a basic helix loop helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co factor for transcriptional regulation by hypoxia inducible factor 1. Chromosomal translocation