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SEN2 Polyclonal Antibody, 20ul Modified Oligos ACYP2 (acylphosphatase 2) encodes the

SKU: 45366608028

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SEN2 Polyclonal Antibody, 20ul Modified Oligos ACYP2 (acylphosphatase 2) encodes theThis gene encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.

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Description

ACYP2 (acylphosphatase 2) encodes the muscle-type isoform (MT)

The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 -alpha-1 - theta1 - 3'

and its activity is mediated by G proteins which activate adenylate cyclase

The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase

but the full-length nature of only three of them have been determined to date

SEN2 Polyclonal Antibody, 20ul Modified Oligos ACYP2 (acylphosphatase 2) encodes theThis gene encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.

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