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Abundant evidence supported the point that TLRs could recognize self- and non-self-antigens accurately as well as promote the phagocytosis of antigens and maturation of dendritic cells (DC) in innate immunity ( LPS/MDP-NLRP3-caspases The activation of the NLRP3 inflammasome by LPS can be achieved by either canonical or non-canonical NLRP3 inflammasome pathways

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Both medications cause similar gastrointestinal side effects, including nausea, constipation, diarrhea, and vomiting

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Researchers once reported metabolically healthy but obese individuals had two- to three-fold higher expressions of genes associated with adipocyte differentiation, though the proportion of small adipocytes was actually lower than metabolically abnormal obese individuals, which may share some similarities with PWS patients [36]

doi:10.1007/s10545-010-9159-6