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doi: 10.3389/fphar.2022.1068495 Received 13 October 2022 Accepted 01 November 2022 Published 14 November 2022 Volume 13 - 2022 Edited by Jie Tang, College of Pharmacy, University of Michigan, United States Reviewed by Jing Sun, Luye Pharm, China Chengyi Li, Michigan Medicine, University of Michigan, United States Updates Copyright 2022 Maeng and Lee

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GLP-Squared Injection combines semaglutide and tirzepatide for dual GLP-1 and GIP receptor activation, producing greater appetite suppression and insulin secretion than single-agent therapy