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In the full cohort, GLP-1 users had 35.1% lower odds of developing breast cancer

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A recent study reported that egl nine homolog 1 (EGLN1) and Myc activate lymphoid-specific helicase (LSH) expression through HIF-1, and that LSH suppresses ferroptosis through the interaction with WDR76, leading to the activation of lipid metabolism-associated genes (Jiang et al., 2017)