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doi: 10.1038/nrneph.2017.123 49 MuskietM

They are not approved for cosmetic use, and their safety profile remains poorly defined

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However, the delivery method is just as important as the tripeptide itself

Interestingly, the primary outcome event rate was more than double in the placebo group (24% at 32 months), compared with what would have been predicted for the average DAPA-CKD patient using the international IgA nephropathy risk prediction tool, suggesting a high-risk group of participants