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ER Alpha Monoclonal Antibody, 50ul[BT-MCA0516] Enzymes Sialomucins are a heterogeneous group

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ER Alpha Monoclonal Antibody, 50ul[BT-MCA0516] Enzymes Sialomucins are a heterogeneous groupThis gene encodes an estrogen receptor, a ligand activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen

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Description

Sialomucins are a heterogeneous group of secreted or membrane-associated mucins that appear to play 2 key but opposing roles in vivo: first as cytoprotective or antiadhesive agents

It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients

which accumulate in the brains of human Alzheimer's disease patients

The protein encoded by EIF3D (eukaryotic translation initiation factor 3 subunit D) is the major RNA binding subunit of the eIF3 complex

A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers

ER Alpha Monoclonal Antibody, 50ul[BT-MCA0516] Enzymes Sialomucins are a heterogeneous groupThis gene encodes an estrogen receptor, a ligand activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen

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