SREBP-1(Phospho Ser439) Polyclonal Antibody, 50ul Immunology The protein is an S-type
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SREBP-1(Phospho Ser439) Polyclonal Antibody, 50ul Immunology The protein is an S-typeThis gene encodes a transcription factor that binds to the sterol regulatory element 1 (SRE1) which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit
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