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RJR-2403 - CAS# 15585-43-0 26481585 324523-20-8 (NPS-2143 hydrochloride)

RJR-2403 - CAS# 15585-43-0 26481585 324523-20-8 (NPS-2143 hydrochloride)

Name: RJR-2403 - CAS# 15585-43-0 26481585 324523-20-8 (NPS-2143 hydrochloride)
Brand: skntheory.com
SKU: 20004228864
Price: 110.00 USD
Availability: InStock
Rating: 4.3645000000000005 (13 reviews)

SKU: 20004228864

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RJR-2403 - CAS# 15585-43-0 26481585 324523-20-8 (NPS-2143 hydrochloride)Metanicotine, also known as RJR 2403 and TC 2403, is a neuronal nicotinic receptor agonist, showing high selectivity for the 42 subtype. Metanicotine has high affinity to rat brain cortex (Ki = 26 + 3 nM). Metanicotine is comparable to nicotine in activating rat thalamic synaptosomes (EC50 = 732 + 155 nM and Emax = 91 + 8% for RJR 2403; EC50 = 591 + 120 nM and Emax = 100 + 25% for nicotine) . Chronic administration of RJR 2403 in combination with low

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Description

324523-20-8 (NPS-2143 hydrochloride)

1530/REP-12-0099

The cumulative change in food intake and weight gain increases dose-dependently

Chemical Name: N-(6-chloro-4-methyl-4-phenyl-2

54(1):284-8

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