Nordihydroguaiaretic acid - CAS# 500-38-9 481585 dimerizes with a small Maf

dimerizes with a small Maf protein (sMaf)

Formula: C20H32ClN3O

Chemical Name: (Z)-ethyl 4-(4-((5-nitrofuran-2-yl)methylene)-3

β-Nicotinamide Adenine Dinucleotide

CCCCCCCCC(=O)N[C@H](CN1CCCC1)[C@H](O)C1=CC2OCCOC=2C=C1

Nordihydroguaiaretic acid - CAS# 500-38-9 481585 dimerizes with a small MafEtrasimod, also known as APD334, is a potent, centrally available, functional antagonists of the S1P1 receptor for use as next generation therapeutics for treating multiple sclerosis (MS) and other autoimmune diseases. APD334 has a favorable PK PD profile, producing robust lymphocyte lowering at relatively low plasma concentrations in several preclinical species. APD334 was efficacious in a mouse experimental autoimmune encephalomyelitis (EAE) model