Efinaconazole - CAS# 164650-44-6 Size:Solid 10 mg 2-methylpropan-2-amine

2-methylpropan-2-amine

an enzyme often overexpressed in cancer cells

Chemical Name: 2-(butylamino)-4-[(4-hydroxycyclohexyl)amino]-N-{[4-(1H-imidazol-1-yl)phenyl]methyl}pyrimidine-5-carboxamide

whereas inhibits total SAPK/JNK activity with an IC50 of 3–10 μM

InChiKey: BXKYFUGAAFLYJL-BXGYHSFXSA-N

Efinaconazole - CAS# 164650-44-6 Size:Solid 10 mg 2-methylpropan-2-amineEfinaconazole is a triazole antifungal. It is approved for use in Canada and the USA as a 10% topical solution for the treatment of onychomycosis (fungal infection of the nail). Efinaconazole acts as a 14 demethylase inhibitor. Efinaconazole inhibits fungal lanosterol 14 demethylase involved in the biosynthesis of ergosterol, a constituent of fungal cell membranes. Efinaconazole has been shown to be active against isolates of the following