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Headaches and dizziness also appear on the side effect list, though they tend to be mild and transient

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Characterization of gut microbiota in prenatal cold stress offspring rats by 16S rRNA sequencing

2 Materials and methods 2.1 Ethics and regulatory compliance We designed our study in accordance with the ARRIVE guidelines (Percie du Sert et al., 2020) and conducted all experiments in compliance with IACUC regulations and the National Research Councils Guide for the Care and Use of Laboratory Animals, with prior approval from the Texas A&M University IACUC (protocol number 2023-0186)

This means that the primary way metformin helps regulate glucose levels is perhaps by directly affecting how glucose is processed in the intestines