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Why Temporary

Homeostatic (SD) food intake Home cages were changed and food was removed from the home cage 1 hour before the start of the experiment

Those already using metformin or berberine are generally advised in community sources to consider a lower MOTS-c dose with closer monitoring consult a clinician

This is especially important because dehydration can make side effects like nausea, dizziness, or fatigue worse

Headache treatment strategies that work during initial medication starts typically remain effective during switches: adequate hydration, consistent meal timing, and over-the-counter pain relief as needed