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Hemolytic anemia may be more prevalent in patients with both MTHFR and B12 deficiency

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Moreover, its shortcomings have been linked to disturbed homocysteine metabolism, which is associated with various conditions including cancer and cardiovascular disease [52, 53]

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If a serious complication arose (say, an immune reaction or a cancer diagnosed down the line), the patient might argue they werent properly warned because the doctor themselves could not know the risks