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The ability of the MD to reduce visceral adiposity while preserving LBM may have important implications in the context of semaglutide therapy, which is known to reduce overall fat but, in some rare cases, also to associate with a LBM loss [68, 69]

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Microglia-astrocyte co-cultures have identified the mechanism of Ex-4-reduced astrocyte activation, which involved inhibiting the cross-talk of induced microglia

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Medications may play a role as well, which is why reviewing your meds with a clinician is important