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HPS-1 Monoclonal Antibody, 100ul Rotator Some of the isoforms contain

SKU: 12358148737

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HPS-1 Monoclonal Antibody, 100ul Rotator Some of the isoforms containThis gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is a component of three different protein complexes termed biogenesis of lysosome related organelles complex (BLOC) 3, BLOC4, and BLOC5. Mutations in this gene are associated with Hermansky Pudlak syndrome type 1. Alternative splicing results in multiple transcript variants. A pseudogene

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Description

Some of the isoforms contain regions of similarity to beta-defensins| a family of antimicrobial peptides

We always got the ~48 kDa in our detection

KLF8 encodes Kruppel like factor 8 which is a member of the Sp/KLF family of transcription factors

In conjunction with complement component 1| q subcomponent| B chain (C1QB)| this gene shows an increase in expression in melanoma cells and may serve as an accurate biomarker for the disease

the interaction seems to be transient and may prevent degradation allowing for heterodimer formation with p50 or p52

HPS-1 Monoclonal Antibody, 100ul Rotator Some of the isoforms containThis gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is a component of three different protein complexes termed biogenesis of lysosome related organelles complex (BLOC) 3, BLOC4, and BLOC5. Mutations in this gene are associated with Hermansky Pudlak syndrome type 1. Alternative splicing results in multiple transcript variants. A pseudogene

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