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4.4 Neonatal hypoxicischemic encephalopathy The pathophysiology of HIE involves hypoxicischemic injury, characterized by perturbations in mitochondrial dynamics and the inhibition of critical energy-producing pathways, including oxidative phosphorylation and fatty acid -oxidation (54)

To maintain a stable expression of human FcRn, 250 g/mL Geneticine selective antibiotic (G418 Sulfate) (Gibco) and 5 g/mL Blasticidin S HCl (Gibco) were added to the culture medium